Heyde’s syndrome is defined by the association of calcified aortic stenosis and gastrointestinal bleeding due to an acquired form of von Willebrand syndrome. Transcatheter aortic valve implantation reverses von Willebrand factor abnormalities and reduces bleeding events. The clinical management is challenging and requires an interdisciplinary approach.
A 52-year-old man was referred to the cardiology consultation by his general physician for work-up. The patient had no particular symptoms, but his family history was relevant.
For diastolic mitral regurgitation to occur, diastolic left ventricular pressure must exceed the left atrial pressure. In the case presented here, this was due to isolated atrial contraction, not followed by a ventricular systole.
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