a FMH Internal Medicine, FMH Cardiology, Sementina, Switzerland
b Ciriè and Ivrea Hospitals, ASL TO4, Italy
c Cardiocentro Ticino, Lugano, Switzerland
Coronary artery aneurysm formation following percutaneous coronary intervention (PCI) with drug-eluting stents is a known, infrequent complication, causing late acquired strut malapposition, a potential trigger for in-stent thrombosis . First generation durable-polymer sirolimus-eluting stents showed a significant association with coronary evaginations on optical coherence tomography (OCT), probably related to the inflammatory and durable polymer .
The Xposition S is a sirolimus-eluting self-apposing coronary stent with a durable polymer that, by passively adapting to variances in vessel diameter, allows for maximal stent apposition.
We herein report the case of a late acquired fusiform aneurysm of the mid-left anterior descending artery (LAD) caused by the passive arterial wall dilatation as a consequence of the implantation of aself-expandable stent.
A 61-year-old patient, with known coronary artery disease, underwent PCI with a self-expandable stent (Stentis XPOSITION S 3.5−4.5 × 27 mm) for an anterior non-ST segment elevation myocardial infarction (NSTEMI) in January 2016. Post-implant OCT showed good apposition of the stent, with a mean vessel diameter of 3.57 mm at the distal edge and 3.67 mm at the proximal edge (fig. 1)
Because of recurrent angina, check-up angiography was performed in March 2018. A fusiform aneurysm of the mid-LAD was discovered. Intravascular ultrasound revealed a uniform dilatation of the vessel with a calibre of 6 mm throughout the whole stented segment, with no evidence of late acquired malapposition (fig. 2), confirming angiographic findings.
This case represents a new, previously undescribed complication after implantation of self-expandable stent, which caused passive arterial wall dilatation.
No financial support and no other potential conflict of interest relevant to this article was reported.
Alessandro Negro, MD, Medical Village, Via Cantonale 38, CH-6928 Manno, negro.alessandro[at]yahoo.it
1 Alfonso F, Pérez-Vizcayno MJ, Ruiz M, Suárez A, Cazares M, Hernández R, et al.Coronary aneurysms after drug-eluting stent implantation: clinical, angiographic, and intravascular ultrasound findings. J Am Coll Cardiol. 2009;53(22):2053–60. doi:. http://dx.doi.org/10.1016/j.jacc.2009.01.069 PubMed
2 Radu MD, Räber L, Kalesan B, Muramatsu T, Kelbæk H, Heo J, et al.Coronary evaginations are associated with positive vessel remodelling and are nearly absent following implantation of newer-generation drug-eluting stents: an optical coherence tomography and intravascular ultrasound study. Eur Heart J. 2014;35(12):795–807. doi:. http://dx.doi.org/10.1093/eurheartj/eht344 PubMed
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